Publication collection
SynBOLD-DisCo corrects susceptibility distortion in functional MRI using the acquired functional data and a structural image. Synthesized undistorted BOLD contrast provides a correction target when reverse phase-encoding scans or field maps are unavailable.
This conference paper introduces SynBOLD-DisCo, using a 3D U-Net to synthesize undistorted BOLD images for fMRI susceptibility correction. It is the proceedings contribution preceding the expanded 2023 journal study.
Simple tasks and model-free analysis reveal widespread time-locked BOLD changes in both gray and white matter. The shape of the response varies across regions and stimuli, indicating that conventional analyses can miss distributed signals when they impose a narrow response model or discard white matter.
White matter has a different BOLD hemodynamic response from gray matter, and the response varies within and between pathways. These differences also relate to diffusion MRI measures of tissue microstructure.
HARFI estimates the directional structure of correlations in white matter BOLD signals without restricting them to a tensor. Its sampling approach reduces orientation bias and represents bending or fanning patterns, providing a functional MRI complement to diffusion-based descriptions of white matter pathways.
