Publication collection
White matter growth charts built from 35,120 brain scans provide reference trajectories from birth to 100 years. The study measures tissue properties and pathway shape across 72 tracts, enabling age- and sex-adjusted comparisons. Public models, processing tools, and shareable derived data support independent use of the charts.
Analyzing spinal cord measurements by cervical level reveals localized changes in relapsing-remitting multiple sclerosis that whole-cord averages can miss. The study combines diffusion and structural measurements within white and gray matter regions. Gray matter atrophy relates to disability, while the measured microstructural changes do not show significant disability associations.
The study tests whether DTI-ALPS measurements specifically reflect diffusion along perivascular spaces. Analyses of high-resolution diffusion and vascular imaging show strong effects of fiber crossings, dispersion, and undulation. These anatomical influences complicate interpreting an ALPS index as a direct measurement of glymphatic function across individuals or groups.
This study compares the development of short association fibers and long-range pathways in 616 participants aged 5.6–21.9 years. Diffusion tensor and NODDI measurements reveal shared age-related patterns alongside distinct features of superficial white matter. The results provide a reference for future studies of atypical development.
